This is a national consortium of placental biologists and clinicians working on placental mechanisms and circulating biomarkers that may be early indicators of pregnancies at risk of a stillbirth.
Priority Area Two leads: Professor Euan Wallace, Professor Vicki Clifton
Novel tests to improve antenatal detection of women at increased risk of stillbirth and other adverse newborn outcome are needed. A national collaboration is being established to identify novel placental biomarkers for pre-clinical testing. An initial one-day workshop held in Brisbane in July 2017 confirmed support for this national project and a second workshop in December 2017 has taken forward this collaboration.
This study aims to evaluate strategies for detecting mothers and babies at an increased-risk of late-pregnancy stillbirth and other adverse pregnancy outcomes. Specific aims include:
- Improving understanding and prediction of decreased fetal movements
- Assessing the role of routine third-trimester ultrasound scanning in reducing adverse outcomes
- Examining the role of PlGF (placental growth factor) in identifying women at-risk
- Assessing barriers to morphology scanning